Prueba de micronúcleos en células bucales. Una revisión

Autores/as

  • JORGE RAÚL COLCHADO CARHUAVILCA UNIVERSIDAD NACIONAL MAYOR DE SAN MARCOS

DOI:

https://doi.org/10.31984/oactiva.v7i1.728

Palabras clave:

Micronúcleos, Mucosa bucal, Pruebas de mutagenicidad, ADN

Resumen

La prueba de micronúcleos se ha convertido en el método más utilizado para evaluar la genotoxicidad de diferentes factores biológicos, físicos y químicos, convirtiéndose poco a poco en un reconocido marcador de daño en el ADN para el biomonitoreo de diversas entidades sistémicas. Esta revisión está enfocada principalmente en la prueba de micronúcleos en células bucales, considerado en la actualidad como una prueba prometedora para ser utilizada como biomarcador de eventos patológicos, por las características que presenta al no ser invasiva, tolerada por lo pacientes y no requerir de una infraestructura compleja, como equipos de cultivo tisular, para llevarla a cabo. Como se sabe el fundamento de esta prueba es la detección de los micronúcleos, los cuales se originan a partir de cromosomas completos o fragmento de cromosomas que fueron rezagados por genotoxinas durante la mitosis.

 

Palabras clave. Micronúcleos, Mucosa bucal, Pruebas de mutagenicidad, ADN.

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Citas

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Publicado

2022-01-31
ESTADISTICAS
  • Resumen 271

Cómo citar

COLCHADO CARHUAVILCA, J. R. (2022). Prueba de micronúcleos en células bucales. Una revisión. Odontología Activa Revista Científica, 7(1), 37–44. https://doi.org/10.31984/oactiva.v7i1.728

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Artículos de revisión bibliográfica