PREVALENCE OF ORAL MYCOSIS BY Candida albicans , IN PATIENTS UNDER TREATMENT AT JOSÉ CARRASCO ARTEAGA HOSPITAL (IESS)

Authors

  • William Mora

DOI:

https://doi.org/10.31984/oactiva.v1i3.204

Keywords:

Prevalence, frequency, fungal infections, Candida albicans, radiotherapy, chemotherapy, cancer

Abstract

AIM Determine the prevalence of oral mycosis by Candida albicans (CA) in patients between 25-65 years of age with
cancer who had radiation therapy (RT) & chemotherapy (CT) in José Carrasco Arteaga hospital 2015. MATERIALS AND
METHODS: In this paper we use a descriptive cross-sectional study. The sample exhibition includes 98 medical records of
patients treated at the José Carrasco Arteaga Hospital from January 2014 to June 2015. RESULTS: From January 2014
to June 2015, 81 medical records of patients who received RT & QT, developed Candida albicans infection, determining
a prevalence of 82.7%; male group recorded 48 members representing 59.25%, the female group recorded 33 members,
reporting their prevalence by 40.75%; patients to the group members "above 60 years old" recorded 46 people, occupying 47%
of the sample. A group of 66 people received RT developed Candida albicans infection. Patients undergoing radiation between
51-70 Gy, 28 individuals were affected, representing 41.5% of the sample establishing as the group with the highest record. A
group of 48 people received QT developed Candida albicans infection; in this group 15 cases were treated with carboplatin
representing 31.3% of the sample, establishing a direct relationship of the drug with the Candida albicans infection. The
frequent location of Candida albicans at the oral mucosa was recorded in 57 cases determining a prevalence of 44.9% of the
sample. CONCLUSIONS: The CA was present on 82.7% patients treated with RT and CT. It manifests more on males than
females. Occurs more frequently in patients over 60 years of age, related to radiation treatments at doses between 51-70 Gy.

Downloads

Download data is not yet available.

References

1 Rueda G F, Hernández S E. Prevalencia de Candida albicans
aislada de la cavidad oral de pacientes con cáncer. Revista
odontológica latinoamericana 2008. Vol 0, num 2, pag 38 –
41;citado 12/7/2015; disponible en: Documento disponible
2 Rodríguez J 1, Miranda J 2, Morejón H 3 y Santana J C4,
Candidiasis de la mucosa bucal. Rev Cubana Estomatologia.
2002 v.39 n.2 citado 3/7/2015 disponible en: Documento
disponible
3 Sapp J P; Eversole L R; Wysocki G P. infecciones micóticas;
patologia oral y maxilofacial contemporanea; segunda
edicion;Pag 204; citado 09/06/15
4 Oddo A, Zuñiga C, Fernandez E, Garcia R; CANDIDA
ALBICANS; blogspost. [internet];2007 citado 10/07/2015;
disponible en: Documento disponible
5 Cancer.Net Editorial Board [INTERNET]. Salivary Gland
Cancer: Risk Factors. Cancer.Net citado 15/12/2015 disponible
en: Documento disponible
6 Cuenca M, Gadea I, Martin E, Pemán J, Poton J, Rodriguez
J L; Diagnostico microbiológico de las micosis y estudios de sensibilidad a los antifúngicos. En: Cercenado E, Cantón
R, editores. Procedimientos en microbiología Clínica. 21va
edición. 2006. p. 15-27.
7 Biasoli M; Candidiasis. En: Martin A, editor. Candidiasis o
Candidosis. [INTERNET]; 14/03/2013. p. 20 – 24
8 Ynca Cahuana J; Candidiasis Boca – Enfermedades Cáncer
– Tratamiento Radioterapia, Universidad Nacional Mayor
de San Marcos 2006. Citado 12/9/2015; disponible en:
Documento disponible
9 Cortés A J. 1 , Cuervo I S.1 , Arroyo P 2 , Quevedo R
2; hallazgos microbiológicos en pacientes con neutropenia
febril; revista colombiana de cancerología 2003; 7(4):5-11;
citado 20/10/2015
10 Correia J B I; da Silva Freire A R, Complicações bucais
da radioterapia em cabeça e pescoço, Revista Brasileira de
Otorrinolaringologia Print version ISSN 0034-7299. vol.72
no.5 SãoPaulo Sept/Oct. 2006; citado 9/9/2015; disponible
en: Documento disponible
11 Böhme A, Karthaus M, Hoelzer D: Antifungal prophylaxis
in neutropenic patients with hematologic malignancies.
Antibiot Chemother 50: 69-78, 2000. Citado 12/07/2015;
disponible en: Documento disponible
12 Mittal BB, Pauloski BR, Haraf DJ, et al.: Swallowing
dysfunction–preventative and rehabilitation strategies in patients
with head-and-neck cancers treated with surgery, radiotherapy,
and chemotherapy: a critical review. Int J Radiat
Oncol Biol Phys 57 (5): 1219-30, 2003.
13 IPRO: tecnología avanzada sobre vida y calidad [Internet].
Córdova IPRO:2011, [CITADO 11/8/2015 disponible
en: Documento disponible
14 ACS: American cancer society [internet]. Radiation treatment;
USA actualizado en 2014; [citado 13/8/2015]; disponible
en: Documento disponible
15 Lalla RV, Latortue MC, Hong CH, et al.: A systematic
review of oral fungal infections in patients receiving
cancer therapy. Support Care Cancer; USA 2010. [internet];[
CITADO15/8/2015]; disponible en: Documento disponible
16 Mota G A, Sociedad Mexicana de oncologia A.C 2012,
[citado 18/08/2015]; disponible en: Documento disponible
17 Castañón Olivares L R. Unidad de Micología Departamento
de Microbiología y Parasitología, Facultad de Medicina,
UNAM lrcastao@unam.mx 10 agosto 2015
18 ASCO: cáncer.net[internet];junta editorial de cáncer.net;
Estados Unidas de America:2005-2014 Amercan Society
of Clinical Oncology (ASCO); citado 28 de septiembre de
2015; disponible en: Documento disponible
19 NIH: instituto nacional del cáncer en EEUU[internet]; USA:
citado 28 de septiembre de 2015; disponible en: Documento
disponible
20 Lazarde LJ: candidiasis multifocal bucal. Acta odontológica
venezolana[internet]; 2003 citado [6/10/2015];41(2); disponible
en: Documento disponible
21 Mujica M.T*, Finquelievich J.L, Jewtuchowicz V, Iovannitti C.A. Prevalencia de Candida albicans y Candida no albicans
en diferentes muestras clínicas. Período 1999-2001 Rev.
argent. microbiol. v.36 n.3 Ciudad Autónoma de Buenos
Aires jul – sep 2004; [citado 28/8/2015] disponible en:
Documento disponible
22 Carrión A.* Rey O; Patología oral asociada a la sequedad
bucal Avances en Odontoestomatología versión impresa
ISSN 0213-1285 Av dontoestomatol vol.30 no.3 Madrid
mayo-jun. 2014;[citado 28/8/2015]; Documento disponible
23 Aguado J M; Ruiz C I, Muñoz P, Mensa J, Almirante
B, Vázquez L; Guidelines for the treatment of invasive
candidiasis and other yeasts; Spanish Society of Infectious
Diseases and Clinical Microbiology (SEIMC) [internet];
Actualized en 2010; citado en 24/9/2015;
24 Raymond J. Fonseca; oral and maxilofacial surgery. Volume
5. USA: editorial Robert V. Walker;2010
25 Corpus K1, Hegeman-Dingle R, Bajjoka I. Candida kefyr,
an uncommon but emerging fungal pathogen: report of two
cases; NCB; pubmed [internet]; 2004 [fecha de consulta
10/10/2015]; Documento disponible
26 Pfaller M. A. , Diekema D. J. , Gibbs D. L. , Newell V.
A. , Nagy E. , Dobiasova S;Candida krusei, a Multidrug-
Resistant Opportunistic Fungal Pathogen: Geographic and
Temporal Trends from the ARTEMIS DISK Antifungal
Surveillance Program, 2001 to 2005; NCBI: journal of
clinical microbiology [internet]; 2008 [fecha de consulta
10/10/2015
27 Quesada C, Murillo L, Ureña M, Vargas E; CANDIDA
DUBLINIENSIS, BINASS; revista médica de costa rica
[internet]; 2007 [ fecha de consulta 10/10/2015];Documento
disponible
28 Paul L. Fidel, Jr.,1,*Jose A. Vazquez,2 and Jack D. Sobel2
; Candida glabrata: Review of Epidemiology, Pathogenesis,
and Clinical Disease with Comparison to C. albicans; NCBI:
Clinical Microbiology Reviews[internet]; 1999 [fecha
de consulta 10/10/2015]; Documento disponible

Published

2018-03-07
ESTADISTICAS
  • Abstract 836
  • PDF (Español (España)) 628
  • HTML (Español (España)) 132

How to Cite

Mora, W. (2018). PREVALENCE OF ORAL MYCOSIS BY Candida albicans , IN PATIENTS UNDER TREATMENT AT JOSÉ CARRASCO ARTEAGA HOSPITAL (IESS). Odontología Activa Revista Científica, 1(3), 23–28. https://doi.org/10.31984/oactiva.v1i3.204