PULP CALCIFICATIONS DUE TO THE USE OF STATINS: LITERATURE REVIEW.
DOI:
https://doi.org/10.31984/oactiva.v7i3.683Keywords:
dental pulp calcifications, denticle, stones dental pulp, Statins, HMG-CoA StatinsAbstract
There is no clear knowledge about the etiology of pulp calcifications. Although the formation of these nodular masses has been related to factors, such as age, alteration of pulp blood supply, genetic predisposition, different dental anomalies, long-term irritants like deep restorations, caries, abrasions, traumas, among others; and among the associated systemic factors, there are different types of syndromes, tumors, cardiovascular diseases related to the intake of drugs like statins. Local application of statins has resulted in dentin formation both in vitro and in vivo, and it is likely that their long-term systemic use may lead to increased tertiary dentin formation and may result in adverse effects such as pulpal calcifications. Thus, this article aims to describe the relationship between the use of statins and pulp calcifications, through the review and analysis of scientific articles.
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