Anemia, iron-deficiency and early childhood caries: Literature review
DOI:
https://doi.org/10.31984/oactiva.v8i2.670Keywords:
Early childhood Caries; Iron-deficiency, anemia; PreschoolAbstract
The objective of this review is to describe the bidirectional relationship between early childhood caries (ECC) and iron-deficiency anemia. Were consulted databases such as Medline, Scielo, Science Direct, Scopus and Taylor & Francis Group; were included cross sectional, case control, case reports and in vitro studies with topics related to early childhood caries and iron deficiency anemia. ECC generates an inflammation that increases the level of cytokines (IL-6 and IL-1) that disrupt iron regulation, the pain of carious lesions reduces chewing efficiency. In addition, in some cases the habit of prolonged consumption of dairy products inhibits intestinal iron absorption; iron forms in enamel an acid layer resistant to demineralization and bacterial colonization, replaces calcium in hydroxyapatite; reduction of iron at the stomatological level alters the functioning of salivary glands and dental pigmentation process. It is concluded that ECC is associated with a higher risk of iron-deficiency anemia. The iron seems to play a fundamental role on the activity of dental caries and it is still necessary to develop further longitudinal section studies that look for a bidirectional association between ECC and iron-deficiency anemia
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